N. Mueller

Validation and Establishment of a SARS-CoV-2 Lentivirus Surrogate Neutralization Assay as a pre-screening tool for the Plaque Reduction Neutralization Test

LGR5 targeting molecules as therapeutic agents for multiple cancer types

This study develops LGR5-targeting antibodies and therapeutics that effectively kill CRC, HCC, and pre-B ALL cancer cells while sparing normal tissues.

ReSurveyGermany: Vegetation-plot time-series over the past hundred years in Germany

The paper compiles and harmonizes vegetation-plot resurvey data from Germany over almost 100 years, enabling analysis of biodiversity change and species distribution shifts.

Inhibiting BCKDK in triple-negative breast cancer suppress protein translation, impair mitochondrial function, and potentiate doxorubicin cytotoxicity

This study shows that inhibiting BCKDK in TNBC cells reduces protein translation, impairs mitochondrial function, and enhances doxorubicin-induced cell death.

Integration of phenomics and transcriptomics data to reveal drivers of inflammatory processes in the skin

The paper integrates phenomics and transcriptomics data from skin samples to identify gene signatures driving inflammatory processes, revealing new factors like CEBPB and PTTG2.

A comparative 'omics approach to candidate pathogenicity factor discovery in the brain-eating amoeba Naegleria fowleri

This study uses -omics approaches to identify candidate pathogenicity factors in Naegleria fowleri by comparing it to its non-pathogenic relative Naegleria gruberi.

Regulation of Hepatic MicroRNAs in Response to Early Stage Echinococcus multilocularis Egg Infection in C57BL/6 mice

This study identifies 28 dysregulated hepatic miRNAs in C57BL/6 mice infected with Echinococcus multilocularis eggs, showing downregulation of miRNAs involved in angiogenesis and fatty acid biosynthesis.