Author

B. Huntly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Garcia-Gimenez· 2 shared G. Giotopoulos· 2 shared S. E. Richardson· 2 shared A. F. Domingues· 1 shared A. Godsinia· 1 shared A. R. Fard· 1 shared C. K. Lopez· 1 shared C. Kapeni· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

A. Garcia-Gimenez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic or pharmacological inactivation of CREBBP sensitizes B-cell Acute Lymphoblastic Leukemia to Ferroptotic Cell Death upon BCL2 Inhibition

A. Garcia-Gimenez, J. E. Ditcham, D. M. A. Azazi, E. Meduri, R. Asby, N. Sakakini, C. K. Lopez, N. Narayan, T. Beinortas, J. Bagri, S. Agrawal Singh, G. Giotopoulos, M. P. Murphy, S. J. Horton, B. Huntly, S. E. Richardson

This study identifies CREBBP mutations as a targetable vulnerability in B-ALL, showing that CREBBP inhibition sensitizes these cells to Venetoclax-induced ferroptosis.

bioRxiv · Oct 2, 2023 · PreprintCancer Biology

LGR5 targeting molecules as therapeutic agents for multiple cancer types

H.-C. Chen, N. Mueller, K. Stott, E. Rivers, C. Kapeni, C. M. Sauer, F. Beke, S. Walsh, N. Ashman, L. M. O'Brien, A. R. Fard, A. Godsinia, F. Joud, O. Giger, I. Zlobec, , M. de la Roche

This study develops LGR5-targeting antibodies and therapeutics that effectively kill CRC, HCC, and pre-B ALL cancer cells while sparing normal tissues.

bioRxiv · Sep 1, 2022 · PreprintCell Biology

Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis

S. Gupta, O. M. Dovey, A. F. Domingues, O. W. Cyran, C. M. Cash, G. Giotopoulos, J. Rak, J. Cooper, M. Gozdecka, R. J. Asby, N. Al-Jabery, V. Hernandez-Hernandez, S. Prabakaran, B. Huntly, G. S. Vassiliou, C. Pina

Loss of Kat2a enhances transcriptional variability of ribosome biosynthetic programs and transiently accelerates pre-leukemia.

bioRxiv · Oct 18, 2021 · PreprintCancer Biology