Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection
Y. Liu, R. Mukherjee, F. Bonn, T. Colby, I. Matic, M. Glogger, M. Heilemann, I. Dikic
This study shows that Legionella's SdeA effector causes Golgi disruption via serine ubiquitination of GRASP55 and GRASP65, affecting the secretory pathway and cytokine release.
bioRxiv · Jul 27, 2020Cell Biology