Author

F. C. Sciurba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. D. Gregory· 2 shared Y. Zhang· 2 shared B. A. Kaufman· 1 shared C. Kliment· 1 shared D. N. Robinson· 1 shared E. DeVallance· 1 shared H. Harvey· 1 shared J. E. Radder· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

A. D. Gregory

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Author profile →

2 papers

Recent·Most cited

Extracellular release of mitochondrial DNA is triggered by cigarette smoke and is detected in COPD

L. Giordano, A. D. Gregory, M. Perez Verdaquer, S. A. Ware, H. Harvey, E. DeVallance, T. Brzoska, P. Sundd, Y. Zhang, F. C. Sciurba, S. D. Shapiro, B. A. Kaufman

This study shows that cigarette smoke triggers mitochondrial DNA release in COPD patients and animal models, linking it to inflammation and disease progression.

bioRxiv · Oct 4, 2021 · PreprintCell Biology

Adenine Nucleotide Translocase regulates the airway epithelium, mitochondrial metabolism and ciliary function

C. Kliment, J. M. K. Nguyen, M. J. Kaltreider, Y.-W. Lu, S. M. Claypool, J. E. Radder, F. C. Sciurba, Y. Zhang, A. D. Gregory, P. A. Iglesias, V. K. Sidhaye, D. N. Robinson

This study identifies Adenine Nucleotide Translocase (ANT) as a protective factor against cigarette smoke in lung cells, showing its role in mitochondrial metabolism, airway hydration, and ciliary function in COPD.

bioRxiv · May 18, 2020 · PreprintCell Biology