Author

C. Kliment

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Y. Zhang· 2 shared A. D. Gregory· 1 shared D. N. Robinson· 1 shared F. C. Sciurba· 1 shared J. C. Boatz· 1 shared J. E. Radder· 1 shared J. M. K. Nguyen· 1 shared J. Sui· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Y. Zhang

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2 papers

Recent·Most cited

Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis

J. C. Boatz, J. Sui, Q. Hu, X. Li, Y. Zhang, M. Koenigshoff, C. Kliment

This study shows that loss of ANT1 increases fibrosis and epithelial cell senescence in IPF by causing mitochondrial dysfunction.

bioRxiv · Sep 9, 2022 · PreprintCell Biology

Adenine Nucleotide Translocase regulates the airway epithelium, mitochondrial metabolism and ciliary function

C. Kliment, J. M. K. Nguyen, M. J. Kaltreider, Y.-W. Lu, S. M. Claypool, J. E. Radder, F. C. Sciurba, Y. Zhang, A. D. Gregory, P. A. Iglesias, V. K. Sidhaye, D. N. Robinson

This study identifies Adenine Nucleotide Translocase (ANT) as a protective factor against cigarette smoke in lung cells, showing its role in mitochondrial metabolism, airway hydration, and ciliary function in COPD.

bioRxiv · May 18, 2020 · PreprintCell Biology