Author

F. Debart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

J.-J. Vasseur· 2 shared A. AMALRIC· 1 shared A. ATTINA· 1 shared A. BASTIDE· 1 shared A. CHOQUET· 1 shared A. DAVID· 1 shared A. Moussa· 1 shared A. Shannon· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

J.-J. Vasseur

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Author profile →

2 papers

Recent·Most cited

Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527

A. Shannon, V. Fattorini, B. Sama, B. Selisko, M. Feracci, C. Falcou, P. Gauffre, P. El Kazzi, E. Decroly, N. Rabah, K. Toulon, C. Eydoux, J.-C. Guillemot, M. Noel, F. Debart, , B. Canard

This paper identifies a protein-priming mechanism for SARS-CoV RNA synthesis and shows that AT-527 inhibits this process by targeting both NiRAN and RdRp domains.

bioRxiv · Mar 23, 2021Biochemistry

FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell

S. RELIER, J. RIPOLL, H. GUILLORIT, A. AMALRIC, F. BOISSIERE, J. VIALARET, A. ATTINA, F. DEBART, A. CHOQUET, F. MACARI, E. SAMALIN, J.-J. VASSEUR, J. PANNEQUIN, E. CRAPEZ, C. HIRTZ, , A. DAVID

This study shows FTO-mediated m6Am demethylation reduces CSC properties in colorectal cancer by affecting translation efficiency, not transcriptome remodeling.

Nature Communications · Mar 19, 2021Peer-reviewedCancer Biology