Cancer BiologybioRxivPreprint
Three-dimensional Genome Organization Maps in Normal Haematopoietic Stem Cells and Acute Myeloid Leukemia
B. Wang, L. Kong, D. Babu…·M. J. Fullwood
This study maps 3D genome organization in normal and AML haematopoietic stem cells, finding increased chromatin loops to oncogenes in AML and identifying MEIS1 and HOXA9 as key oncogenes regulated by these interactions.