Author

F. Hackett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Organism:plant (other)· 1

Frequent Co-Authors

M. Blackman· 2 shared A. Adibekian· 1 shared A. P. Snijders· 1 shared A. Ramaprasad· 1 shared A. Sait· 1 shared C. R. Collins· 1 shared C. Withers-Martinez· 1 shared D. A. Fidock· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

M. Blackman

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3 papers

Recent·Most cited

Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets

J. M. Bennett, S. K. Narwal, S. Kabeche, D. Abegg, F. Hackett, T. Yeo, V. Li, R. K. Muir, F. F. Faucher, S. Lovell, M. Blackman, A. Adibekian, E. Yeh, D. A. Fidock, M. Bogyo

The paper identifies mixed alkyl/aryl phosphonates as anti-malarial compounds that inhibit serine hydrolases with low resistance potential.

bioRxiv · Jan 11, 2024Microbiology

A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite

A. Ramaprasad, P.-C. Burda, E. Calvani, A. Sait, S. A. Palma-Duran, C. Withers-Martinez, F. Hackett, J. I. MacRae, L. Collinson, T. Gilberger, M. Blackman

This study identifies PfGDPD as a choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in Plasmodium falciparum.

bioRxiv · Jun 14, 2022Microbiology

The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion

C. R. Collins, F. Hackett, S. A. Howell, A. P. Snijders, M. R. Russell, L. M. Collinson, M. J. Blackman

This study shows that the malaria parasite's SUB2 protease is essential for shedding surface proteins during RBC invasion and for sealing the host cell membrane.

bioRxiv · Jul 15, 2020Microbiology