M. J. Blackman

This study identifies LCAT as a key enzyme required for efficient egress of malaria parasites from red blood cells during the asexual blood stage.

The paper identifies essential phospholipases in Plasmodium falciparum, showing PF3D7_1013500 is critical for parasite maturation and PF3D7_1358000 is vital for mitochondrial function and growth.

This study shows malaria parasites synchronize their asexual replication with host daily rhythms via the essential amino acid isoleucine, which is periodically supplied through host feeding.

This study identifies ICM1, a multipass membrane protein interacting with PKG in malaria parasites, and shows it regulates calcium signals critical for gametogenesis and parasite survival.

This study shows that the malaria parasite's SUB2 protease is essential for shedding surface proteins during RBC invasion and for sealing the host cell membrane.

This study identifies PV5, a lipocalin-like protein, as critical for controlling haem crystallization into haemozoin in malaria parasites, with implications for drug development.