Author

F. Hetzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

B. Kobilka· 1 shared G. Skiniotis· 1 shared H. Huebner· 1 shared H. Wang· 1 shared J. Kaindl· 1 shared J. Meyerowitz· 1 shared P. Gmeiner· 1 shared Q. Qu· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. Kobilka

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1 paper

Recent·Most cited

Structure-based Evolution of G protein-biased μ-opioid Receptor Agonists

H. Wang, F. Hetzer, W. Huang, Q. Qu, J. Meyerowitz, J. Kaindl, H. Huebner, G. Skiniotis, B. Kobilka, P. Gmeiner

The paper reports cryoEM structures of the μ-opioid receptor bound to biased agonists PZM21 and FH210, revealing structural basis for reduced β-arrestin recruitment and guiding development of safer analgesics.

bioRxiv · Mar 22, 2022Pharmacology & Toxicology