Author

F. Hollande

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. G. Heriot· 2 shared C. Behrenbruch· 2 shared C. Shembrey· 2 shared M. Foroutan· 2 shared S. M. Grimmond· 2 shared A. Preaudet· 1 shared A. Puisieux· 1 shared A. W. Burgess· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

A. G. Heriot

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3 papers

Recent·Most cited

A new highly-specific Natural Killer cell-specific gene signature predicting recurrence in colorectal cancer patients.

C. Shembrey, C. Behrenbruch, B. P. Loveday, A. G. Heriot, M. Foroutan, F. Hollande

This paper develops a CRC-specific NK cell gene signature that predicts recurrence in colorectal cancer patients by identifying high NK cell activity associated with improved survival.

bioRxiv · Apr 29, 2022Cancer Biology

TGF-beta1 induced S100 family protein expression is associated with epithelial to mesenchymal transition states and poor survival in pancreatic cancer

R. R. J. Low, K. Y. Fung, H. Gao, A. Preaudet, L. F. Dagley, J. Yousef, B. Lee, R. H. Larsen, N. J. Kershaw, A. W. Burgess, P. Gibbs, F. Hollande, M. D. W. Griffin, S. M. Grimmond, T. L. Putoczki

The paper links TGF-beta1-induced S100 family protein expression to EMT states and poor survival in pancreatic cancer using a murine organoid biobank.

bioRxiv · Feb 25, 2022 · PreprintCancer Biology

Targeting of TP53-independent cell cycle checkpoints overcomes FOLFOX resistance in Metastatic Colorectal Cancer

C. Behrenbruch, M. Foroutan, P. Lind, J. Smith, M. Grandin, B. Cooper, C. Shembrey, S. Ramm, K. Cowley, I. Nikolic, J. Liuu, J. Cursons, R. Millen, A.-M. Patch, N. D. Huntington, , F. Hollande

This study identifies FOLFOX resistance in metastatic CRC through cell cycle checkpoint dysregulation and shows that targeting these checkpoints can resensitize resistant organoids to FOLFOX.

bioRxiv · Feb 4, 2021 · PreprintCancer Biology