Author

A. Badache

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

P. Verdier-Pinard· 3 shared A. Llewellyn· 2 shared D. Salaün· 2 shared F. Iv· 2 shared M. Belhabib· 2 shared M. Gomes· 2 shared M. Kuzmic· 2 shared M. Mavrakis· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

P. Verdier-Pinard

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Human septins in cells organize as octamer-based filaments mediating actin-membrane anchoring

C. S. Martins, C. Taveneau, G. Castro-Linares, M. Baibakov, N. Buzhinsky, M. Eroles, V. Milanovic, F. Iv, L. Bouillard, A. Llewellyn, M. Gomes, M. Belhabib, M. Kuzmic, P. Verdier-Pinard, S. Lee, , M. Mavrakis

This study shows that human septins form octamer-based filaments that mediate actin-membrane anchoring, as demonstrated through various imaging and biophysical techniques.

bioRxiv · Feb 23, 2022Cell Biology

Septin-microtubule association requires a MAP-like motif unique to Sept9 isoform 1 embedded into septin octamers

M. Kuzmic, G. Castro Linares, J. Leischner Fialova, F. Iv, D. Salaün, A. Llewellyn, M. Gomes, M. Belhabib, Y. Liu, K. Asano, T. Tachibana, G. Koenderink, A. Badache, M. Mavrakis, P. Verdier-Pinard

The paper identifies a MAP-like motif in Sept9 isoform 1 that drives septin-microtubule interaction and shows how HNA mutations disrupt this association.

bioRxiv · Apr 6, 2021 · PreprintCell Biology

Structural and dynamic characterization of the C-terminal tail of ErbB2: disordered but not random

L. Pinet, Y. Wang, C. Deville, E. Lescop, A. Badache, F. Bontems, N. Morellet, D. Durand, F. Guerlesquin, N. Assrir, C. van Heijenoort

This study characterizes the disordered C-terminal tail of ErbB2 at atomic resolution, revealing structural features that suggest functional roles in auto-regulation and protein interactions.

bioRxiv · Sep 9, 2020Biophysics

iASPP contributes to cortex rigidity, astral microtubule capture and mitotic spindle positioning

A. Mangon, D. Salaün, M. Lala Bouali, S. Quitard, D. Isnardon, S. Audebert, P.-H. Puech, P. Verdier-Pinard, A. Badache

This study shows iASPP interacts with EB1 and Myo1c to regulate cortical rigidity, microtubule capture, and spindle positioning during mitosis.

bioRxiv · Dec 10, 2019Cell Biology

A proximity-labeling proteomic approach to investigate invadopodia molecular landscape in breast cancer cells

S. THUAULT, C. Mamelonet, J. SALAMEH, K. OSTACOLO, B. CHANEZ, D. SALAUN, E. BAUDELET, S. Audebert, L. CAMOIN, A. BADACHE

The paper develops a proteomic approach using BioID to identify invadopodia components in breast cancer cells, revealing novel Tks5 partners and their role in actin cytoskeleton organization.

bioRxiv · Dec 10, 2019Cancer Biology