G. H. Koenderink

The paper engineers a recombinant actin-vimentin crosslinker, ACTIF, which forms composite bundles and stiffens actin-vimentin networks, demonstrating modularity in crosslinker design.

This study evaluates composite hydrogels of hyaluronan and fibrin to assess their impact on mesenchymal stromal cell shape and chondrogenesis in 3D environments.

This study investigates how water isotopes affect collagen self-assembly by comparing D2O and H2O, finding faster assembly and thinner fibrils in D2O due to reduced hydration.

This study shows that human septins form octamer-based filaments that mediate actin-membrane anchoring, as demonstrated through various imaging and biophysical techniques.

DisGUVery automates GUV image analysis, enabling fast and consistent quantitative assessment across diverse imaging sources and experiments.

This paper shows that passive cross-linkers between actin and growing microtubules generate forces that transport actin filaments, revealing a new mechanism for actin remodeling.

This study investigates how hyaluronan's molecular weight affects its surface accumulation at water/air interfaces and its interaction with water molecules.

This study shows membrane binding enables fly septins to form ordered filamentous arrays, with C-terminal regions required for stacking.

This study investigates how calcium ions bind to hyaluronan, reducing its chain rigidity through specific molecular interactions.

This study resolves the molecular packing structure of fibrin fibers using X-ray scattering and molecular modeling, revealing key structural features that explain their mechanical properties.

This study uses in situ X-ray scattering to reveal how fibrin's molecular structure contributes to its extensibility under shear strain, showing that fiber elongation arises from uncoiling of disordered C-peptide linkers.

This paper introduces a semi-automated tracking algorithm to analyze molecular packing density of protein filaments using STEM images, revealing structural details of actin, microtubules, and collagen.

The paper measures crosslinker unbinding rates in actin networks using rheology and FRAP, finding a discrepancy between the two methods and attributing it to the mechanical properties of biopolymers.

The paper introduces an open-source software tool for automated tracking of biopolymer networks in 2D and 3D using stretching open active contours, demonstrating its application in live cell studies.

The paper investigates how myosin-driven polarity sorting remodels actin-myosin networks, showing that end-dwelling leads to contraction in quasi-2D networks.