Increased pulmonary monocyte infiltration and attenuated phagocytosis defines perinatal dysfunction of innate immunity in Cystic Fibrosis
F. Jaudas, F. Bartenschlager, B. Shashikadze, G. Santamaria, A. Schnell, N. Naumann-Barsch, H. Bruns, S. Y. Graeber, A. Baehr, M. Cambra-Bort, M. Stirm, J. B. Stoeckl, S. Krebs, H. Blum, C. Schulz, , N. Klymiuk
The paper identifies increased monocyte infiltration and reduced phagocytosis in CF lungs at birth, suggesting innate immune dysfunction and the need for early treatment.
bioRxiv · Sep 11, 2023 · PreprintImmunology