Author

H. Bruns

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:flow cytometry· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

M. Büttner-Herold· 2 shared A. Baehr· 1 shared A. Broijl· 1 shared A. Gerbitz· 1 shared A. Mackensen· 1 shared A. Moosmann· 1 shared A. Moretti· 1 shared A. Saalmueller· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

M. Büttner-Herold

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Author profile →

4 papers

Recent·Most cited

Increased pulmonary monocyte infiltration and attenuated phagocytosis defines perinatal dysfunction of innate immunity in Cystic Fibrosis

F. Jaudas, F. Bartenschlager, B. Shashikadze, G. Santamaria, A. Schnell, N. Naumann-Barsch, H. Bruns, S. Y. Graeber, A. Baehr, M. Cambra-Bort, M. Stirm, J. B. Stoeckl, S. Krebs, H. Blum, C. Schulz, , N. Klymiuk

The paper identifies increased monocyte infiltration and reduced phagocytosis in CF lungs at birth, suggesting innate immune dysfunction and the need for early treatment.

bioRxiv · Sep 11, 2023 · PreprintImmunology

An IL-1β driven neutrophil-stromal cell axis fosters a BAFF-rich microenvironment in multiple myeloma

M. M. de Jong, C. Fokkema, N. Papazian, T. van Heusden, M. Vermeulen, R. Hoogenboezem, G. van Beek, S. Tahri, M. A. Sanders, P. van de Woestijne, F. Gay, P. Moreau, M. Büttner-Herold, H. Bruns, M. van Duin, , T. Cupedo

The paper identifies a neutrophil-stromal cell feedback loop in multiple myeloma that promotes BAFF-rich inflammation, persisting after treatment and suggesting dual targeting strategies.

bioRxiv · Mar 3, 2023 · PreprintImmunology

Reconstitution of T cell immunity against EBV in the immunocompromised host by adoptive transfer of peptide-stimulated T cells after allogeneic stem cell transplantation

M. F. Lammoglia Cobo, J. Ritter, R. Gary, V. Seitz, J. Mautner, M. Aigner, S. Völkl, S. Schaffer, S. Moi, A. Seegebarth, H. Bruns, W. Rösler, K. Amann, M. Büttner-Herold, S. Hennig, , A. Gerbitz

The paper demonstrates that adoptive transfer of peptide-stimulated donor-derived EBV-specific T cells can reconstitute EBV-specific immunity and control EBV reactivation in an immunocompromised patient post-transplant.

bioRxiv · Dec 16, 2021 · PreprintImmunology

Loss of TP53 mediates suppression of Macrophage Effector Function via Extracellular Vesicles and PDL1 towards Resistance against Chemoimmunotherapy in B-cell malignancies

E. Izquierdo, D. Vorholt, B. Sackey, J. Nolte, S. J. Blakemore, J. Schmitz, V. Barbarino, N. Nickel, D. Bachurski, L. Lobastova, M. Nikolic, M. Michalik, R. Brinker, R. Neuhaus, L. Frenzel, , C. Pallasch

This paper identifies that TP53 loss in B-cell lymphoma leads to resistance against chemoimmunotherapy by suppressing macrophage effector function through PDL1-expressing extracellular vesicles.

bioRxiv · Jun 11, 2020 · PreprintCell Biology