BiochemistrybioRxivPreprint
PNPO-PLP Axis Senses Prolonged Hypoxia by Regulating Lysosomal Activity
H. Sekine, H. Takeda, A. Kishino…·H. Motohashi
The paper identifies the PNPO-PLP axis as a mechanism for sensing prolonged hypoxia by regulating lysosomal activity in macrophages, leading to altered inflammatory responses.
DOI 10.1101/2022.10.28.514185