Author

N. Ota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 2 Animal Behavior & Cognition· 1 Biochemistry· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:deep learning· 2 Research Focus:ecology & biodiversity· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

M. Yamamoto· 3 shared F. Katsuoka· 2 shared H. Anzawa· 2 shared H. Motohashi· 2 shared H. Sekine· 2 shared K. Ishida· 2 shared K. Kinoshita· 2 shared Z. Liu· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

M. Yamamoto

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Evidence that recent climatic changes have expanded the potential geographical range of the Mediterranean fruit fly

A. M. Szyniszewska, H. Bieszczak, K. Kozyra, N. T. Papadopoulos, M. De Meyer, J. Nowosad, N. Ota, D. J. Kriticos

The paper assesses climate change impacts on the Mediterranean fruit fly's range expansion in Europe and California using a CLIMEX model and climate data.

bioRxiv · Nov 15, 2023Ecology

Deep learning for histopathological subtyping and grading of lung adenocarcinoma

K. Lami, N. Ota, S. Yamaoka, A. Bychkov, K. Matsumoto, W. Uegami, R. Attanoos, S. Berezowska, L. Brcic, A. Cavazza, J. English, A. T. Fabro, K. Ishida, Y. Kashima, Y. Kitamura, , J. Fukuoka

This study develops CNNs to subtype and grade lung adenocarcinoma, achieving high accuracy and outperforming most pathologists in grading prediction.

bioRxiv · Nov 2, 2022 · PreprintPathology

PNPO-PLP Axis Senses Prolonged Hypoxia by Regulating Lysosomal Activity

H. Sekine, H. Takeda, A. Kishino, H. Anzawa, T. Isagawa, N. Ota, N. Kato, S. Kimura, Z. Liu, K. Kato, F. Katsuoka, M. Yamamoto, F. Miura, T. Ito, M. Takahashi, , H. Motohashi

The paper identifies the PNPO-PLP axis as a mechanism for sensing prolonged hypoxia by regulating lysosomal activity in macrophages, leading to altered inflammatory responses.

bioRxiv · Oct 28, 2022 · PreprintBiochemistry

Enhancer Remodeling Promotes Tumor-Initiating Activity in NRF2-Activated Non-Small Cell Lung Cancers

K. Okazaki, H. Anzawa, Z. Liu, N. Ota, H. Kitamura, Y. Onodera, M. M. Alam, D. Matsumaru, T. Suzuki, F. Katsuoka, S. Tadaka, I. Motoike, M. Watanabe, A. Sakurada, Y. Okada, , H. Motohashi

The paper identifies NRF2-CEBPB cooperativity in promoting tumor-initiating activity in NRF2-activated NSCLCs through enhancer remodeling and the NRF2-NOTCH3 regulatory axis.

bioRxiv · Apr 24, 2020Cancer Biology

Supporting global biodiversity assessment through high-resolution macroecological modelling: Methodological underpinnings of the BILBI framework

A. J. Hoskins, T. D. Harwood, C. Ware, K. J. Williams, J. J. Perry, N. Ota, J. R. Croft, D. K. Yeates, W. Jetz, M. Golebiewski, A. Purvis, T. Robertson, S. Ferrier

The paper introduces BILBI, a framework for high-resolution macroecological modelling of biodiversity patterns, refining beta-diversity mapping using generalized dissimilarity modelling across global species data.

bioRxiv · Jun 4, 2019Ecology

Coffee polyphenols prevent cognitive dysfunction and suppress amyloid β plaques in APP/PS2 transgenic mouse

K. Ishida, M. Yamamoto, K. Misawa, N. Ota, A. Shimotoyodome

This study shows coffee polyphenols prevent cognitive dysfunction and reduce amyloid β plaques in APP/PS2 mice by degrading amyloid β fibrils.

bioRxiv · Jun 15, 2018Animal Behavior & Cognition