Correcting dilated cardiomyopathy with fibroblast-targeted p38 deficiency
R. C. Bretherton, I. M. Reichardt, K. A. Zabrecky, A. J. Goldstein, L. R. J. Bailey, D. Bugg, T. S. McMillen, K. B. Kooiker, G. Flint, A. Martinson, J. Gunaje, F. Koser, W. A. Linke, M. Regnier, F. Moussavi-Harami, , J. Davis
This study shows that targeting p38 in cardiac fibroblasts can reverse fibrosis and improve cardiomyocyte function in a mouse model of dilated cardiomyopathy.
bioRxiv · Jan 23, 2023 · PreprintCell Biology