Author

F. Lam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A. Canette· 1 shared A. Fischer· 1 shared A. Gautier· 1 shared A. Karaiskou· 1 shared A. T. Gimbel· 1 shared C. Bergonzi· 1 shared C. Botuha· 1 shared C. Cao· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiochemistry

A. Canette

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Multiplexed in vivo imaging with fluorescence lifetime modulating tags

L. El Hajji, F. Lam, M. Avtodeeva, H. Benaissa, C. Rampon, M. Volovitch, S. Vriz, A. Gautier

This paper introduces FAST tags that modulate fluorescence lifetime to enable multiplexed imaging of up to six targets in live cells and zebrafish embryos.

bioRxiv · Apr 12, 2024Cell Biology

The aging-induced long non-coding RNA MIRIAL controls endothelial cell and mitochondrial function

C. Kohnle, S. Koziarek, T. Warwick, K. Theodorou, A. Fischer, R. P. Juni, M. Muhly Reinholz, D. Busscher, F. Lam, F. Vetter, J. U. G. Wagner, J. Sommer, A. T. Gimbel, L. Stanicek, S. Guenther, , R. A. Boon

This paper identifies MIRIAL as an aging-induced lncRNA that regulates endothelial quiescence and mitochondrial function through a novel triplex mechanism.

bioRxiv · Feb 28, 2024 · PreprintCell Biology

Integrative Multiscale Biochemical Mapping of the Brain via Deep-Learning-Enhanced High-Throughput Mass Spectrometry

Y. R. Xie, D. C. Castro, S. S. Rubakhin, T. J. Trinklein, J. V. Sweedler, F. Lam

The paper introduces MEISTER, a framework for brain-wide and single-cell biochemical mapping using deep learning and mass spectrometry, identifying region-specific and cell-specific lipid profiles in rat brain tissue.

bioRxiv · May 31, 2023 · PreprintBiochemistry

Identification of the Intracellular Protein Targets of a Bio-active Clickable Half-Sandwich Iridium Complex by Chemical Proteomics

R. Ramos, A. Karaiskou, C. Botuha, M. Trichet, F. Dingli, J. Forte, F. Lam, A. Canette, C. Chaumeton, M. Salome, T. Chenuel, C. Bergonzi, P. Meyer, S. Bohic, D. Loew, , J. Sobczak-Thepot

This study identifies intracellular protein targets of a clickable iridium complex using chemical proteomics, revealing dual electrophilic and oxidative stress mechanisms.

bioRxiv · May 24, 2023 · PreprintBiochemistry

Epigenetic MRI: Noninvasive Imaging of DNA Methylation in the Brain

F. Lam, J. Chu, J. S. Choi, C. Cao, T. K. Hitchens, S. K. Silverman, Z.-P. Liang, R. N. Dilger, G. E. Robinson, K. C. Li

This paper introduces eMRI, a noninvasive method to image DNA methylation in the brain, revealing regional differences in global DNA methylation in pigs.

bioRxiv · Aug 20, 2021Bioengineering