A. Gautier

Multiplexed in vivo imaging with fluorescence lifetime modulating tags

This paper introduces FAST tags that modulate fluorescence lifetime to enable multiplexed imaging of up to six targets in live cells and zebrafish embryos.

A tunable and versatile chemogenetic near infrared fluorescent reporter

The paper introduces nirFAST, a tunable NIR fluorescent reporter for multiplexed imaging, enabling subdiffraction resolution and cell cycle monitoring in live cells.

Simultaneous detection of membrane contact dynamics and associated Ca2+ signals by reversible chemogenetic reporters

The paper introduces PRINCESS, a novel biosensor that simultaneously detects membrane contact sites and measures associated Ca2+ dynamics using splitFAST technology.

Humans progressively feel agency over events triggered before their actions

The paper investigates how humans adapt their sense of agency when consequences precede their actions in an AI-assisted environment, finding implicit learning occurs within an hour.

A tripartite chemogenetic fluorescent reporter: design and evaluation for visualizing ternary protein complexes

The paper designs and evaluates a tripartite chemogenetic fluorescent reporter to visualize ternary protein complexes in live cells.

Improving split reporters of protein-protein interactions through orthology-based protein engineering

The paper improves a split reporter for detecting protein-protein interactions using orthology-based protein engineering, resulting in a brighter, more reliable reporter with higher dynamic range.

A fluorogenic chemically induced dimerization technology for controlling, imaging and sensing protein proximity

This paper introduces CATCHFIRE, a chemically induced dimerization technology that enables real-time monitoring of protein proximity with fluorescence imaging and sensing capabilities.

The salivary protein Saglin facilitates efficient midgut colonization of Anopheles mosquitoes by malaria parasites

This study shows that the salivary protein Saglin aids Plasmodium colonization of the mosquito midgut but not salivary glands, and is ingested with blood to affect parasite development.

Reciprocal regulation of Shh trafficking and H2O2 levels via a noncanonical BOC-Rac1 pathway

This study shows H2O2 levels regulate Shh trafficking and that Shh controls H2O2 synthesis via a noncanonical BOC-Rac1 pathway, impacting tissue patterning.

Visualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST

This study uses FAST, a chemogenetic fluorescent reporter, to visualize exported bacterial proteins in live imaging, demonstrating its functionality on both diderm and monoderm bacteria.

Fluorescent secreted bacterial effectors reveal active intravacuolar proliferation of Listeria monocytogenes in epithelial cells

The paper develops a fluorescent reporter to track secreted bacterial effectors and reveals that Listeria monocytogenes can proliferate intravacuolarly in epithelial cells.