R. Ramos

Age-related spatial ecology of Audouin's gull during the non-breeding season

This study compares migratory patterns, habitat selection, and foraging behavior between juvenile and adult Audouin's gulls during the non-breeding season, finding age-related differences in migration distance, habitat use, and foraging strategies.

Identification of the Intracellular Protein Targets of a Bio-active Clickable Half-Sandwich Iridium Complex by Chemical Proteomics

This study identifies intracellular protein targets of a clickable iridium complex using chemical proteomics, revealing dual electrophilic and oxidative stress mechanisms.

Cross regulation between the molecular clock and kidney inflammatory, metabolic and fibrotic responses

This study investigates the interaction between the molecular clock and kidney fibrosis in experimental models, finding that clock components influence inflammation and fibrosis, while fibrosis alters clock gene expression.

A patient-driven clinicogenomic partnership through the Metastatic Prostate Cancer Project

The paper describes a patient-driven initiative that collects clinicogenomic data from metastatic prostate cancer patients, revealing consistent patient-reported data and genomic insights from cfDNA samples.

Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma

This study evaluates CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma, finding they reduce tumor growth and improve survival by inducing cell cycle arrest and senescence.

Genomic and anatomical comparisons of skin support independent adaptation to life in water by cetaceans and hippos

This study compares genomic and anatomical features of cetaceans and hippos to determine if aquatic adaptations evolved independently or from a common ancestor.

Allelic Variation of MYB10 is the Major Force Controlling Natural Variation of Skin and Flesh Color in Strawberry (Fragaria spp.) fruit

This study identifies MYB10 allelic variation as the primary driver of natural color variation in strawberry fruit, with specific mutations affecting anthocyanin biosynthesis in both diploid and octoploid species.

Cystic fibrosis transmembrane conductance regulator (CFTR) inhibition results in mucus accumulation in human airway epithelia Calu-3 cells: Experimental and Machine Learning Studies

This study uses electron microscopy and machine learning to show that CFTR inhibition reduces secretory vesicle swelling and mucin release in Calu-3 cells, leading to mucus accumulation.

Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis

This study shows that overexpressing Cpt1a in renal tubular epithelial cells reduces fibrosis by restoring mitochondrial function and bioenergetics in CKD models and human patients.

Differential expansion microscopy

This paper introduces differential expansion microscopy (DiExM) to measure anisotropic expansion in biological specimens, revealing subcellular structural distortions during expansion.

A novel combination of chemotherapy and immunotherapy controls tumor growth in mice with a human immune system

This study shows that combining anti-ICOS mAb with chemotherapy reduces tumor growth in humanized mice by enhancing CD8+ T cell activity and reducing Treg numbers.