PhysiologybioRxiv
Myosin essential light chain 1sa decelerates actin and thin filament gliding on β-myosin molecules
J. Osten, M. Mohebbi, P. Uta…·T. Scholz
The paper shows that MLC1sa in soleus myosin slows actin gliding compared to MLC1sb/v in ventricular myosin, likely due to increased actin affinity and reduced dissociation rate.
DOI 10.1085/jgp.202213149