ImmunologybioRxivPreprint
Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic metabolism to fuel growth.
S. Kesvari, J. Masson, M. Ferrari-Cestari…·K. M. Irvine
This study shows that CSF1 increases tissue macrophages and alters systemic metabolism, including glucose uptake and fat mobilization, with reversible effects on liver size and body composition.
DOI 10.1101/2023.05.17.538022