Author

D. Hume

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Forrest· 1 shared A. Pettit· 1 shared A. Tomoiu· 1 shared B. Tse· 1 shared B. Wang· 1 shared C. Stutz· 1 shared F. Nooru-Mohamed· 1 shared FANTOM 5 Consortium· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Forrest

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2 papers

Recent·Most cited

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic metabolism to fuel growth.

S. Kesvari, J. Masson, M. Ferrari-Cestari, L.-G. Bodea, F. Nooru-Mohamed, B. Tse, K. Sokolowski, L. Batoon, O. Patkar, M. Sullivan, H. Ebersbach, C. Stutz, R. Parton, A. Pettit, D. Hume, K. M. Irvine

This study shows that CSF1 increases tissue macrophages and alters systemic metabolism, including glucose uptake and fat mobilization, with reversible effects on liver size and body composition.

bioRxiv · May 17, 2023 · PreprintImmunology

Comprehensive characterisation of molecular host-pathogen interactions in influenza A virus-infected human macrophages

S. Clohisey, N. Parkinson, B. Wang, N. Bertin, H. Wise, A. Tomoiu, K. Summers, P. Carninci, A. Forrest, Y. Hayashizaki, P. Digard, D. Hume, J. K. Baillie, FANTOM 5 Consortium

This study characterizes molecular host-pathogen interactions in influenza A virus-infected human macrophages using CAGE sequencing, revealing snatching preferences and avoidance patterns of host RNAs.

bioRxiv · Jun 17, 2019 · PreprintImmunology