Author

A. Pettit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

B. Jose· 2 shared D. Girard· 2 shared F. Genet· 2 shared H.-W. Tseng· 2 shared J. Gueguen· 2 shared J.-P. Levesque· 2 shared K. Alexander· 2 shared L. Batoon· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPathology

B. Jose

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic metabolism to fuel growth.

S. Kesvari, J. Masson, M. Ferrari-Cestari, L.-G. Bodea, F. Nooru-Mohamed, B. Tse, K. Sokolowski, L. Batoon, O. Patkar, M. Sullivan, H. Ebersbach, C. Stutz, R. Parton, A. Pettit, D. Hume, K. M. Irvine

This study shows that CSF1 increases tissue macrophages and alters systemic metabolism, including glucose uptake and fat mobilization, with reversible effects on liver size and body composition.

bioRxiv · May 17, 2023 · PreprintImmunology

Spinal cord injury reprograms muscle fibro-adipogenic progenitors to formheterotopic bones within muscles

H.-W. Tseng, D. Girard, K. Alexander, S. Millard, F. Torossian, A. Anginot, W. Fleming, J. Gueguen, M.-E. Goriot, D. Clay, B. Jose, B. Nowlan, A. Pettit, M. Salga, F. Genet, , J.-P. Levesque

This study identifies fibro-adipogenic progenitors (FAPs) as the cells-of-origin for neurogenic heterotopic ossifications (NHO) following spinal cord injury, showing their reprogramming into osteoblasts.

bioRxiv · Nov 4, 2021 · PreprintPathology

Interleukin-1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification

H.-W. Tseng, I. Kulina, D. Girard, J. Gueguen, C. Vaquette, M. Salga, W. Fleming, B. Jose, S. Millard, A. Pettit, K. Schroder, G. Thomas, L. Wheeler, F. Genet, S. Banzet, , J.-P. Levesque

This study shows IL-1 signaling promotes neurogenic heterotopic ossification in mice and humans by activating fibro-adipogenic progenitors.

bioRxiv · Oct 19, 2021Physiology

Osteomacs support osteoclast-mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model

L. Batoon, S. M. Millard, L. J. Raggatt, A. C. Wu, S. Kaur, L. W. H. Sun, K. Williams, C. Sandrock, P. Y. Ng, M. Bartnikowski, V. Glatt, N. Pavlos, A. Pettit

This study identifies osteomacs as supporting osteoclast-mediated bone resorption and contributing to osteoporosis in a postmenopausal mouse model.

bioRxiv · Feb 5, 2021Immunology