Author

Fauna L. Smith

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Biology Disciplines

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Immunology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

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Hannah P. Savage· 1 shared Kathrin KläseneriD· 1 shared Michael Reth· 1 shared Nicole BaumgarthiD· 1 shared Zheng Luo· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperImmunology

Hannah P. Savage

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintApr 2, 2019

TLR-induced reorganization of the IgM-BCR complex regulates B-1 cell responses to infections

Hannah P. Savage, Kathrin Kläsener, Fauna L. Smith…·Nicole Baumgarth

This study shows TLR activation in CD5+ B-1 cells reorganizes the IgM-BCR complex, leading to CD5 loss and increased BCR signaling, which is necessary for plasmablast differentiation during infections.

DOI 10.1101/595694

mouseproteomics

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