Author

Fengyi Dong

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Anit ShahiD· 2 shared Aparajeeta MajumderiD· 2 shared Carolann L. EspyiD· 2 shared Eno‐Obong EssieniD· 2 shared Jacob Samuel BrenneriD· 2 shared Jacob W. MyersoniD· 2 shared Jeremy B. KatzeniD· 2 shared Jichuan WuiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Anit ShahORCID

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2 papers

Recent·Most cited

BioengineeringAdvanced SciencePeer-reviewedJan 20, 2026

Targeting DNA-LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman…·Jacob Samuel Brenner

This study shows that targeting DNA-LNPs to endothelial cells enhances transgene expression magnitude, duration, and specificity in target organs.

6 citationstop 2%

mouseDNA methylation

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BioengineeringNature NanotechnologyPeer-reviewedAug 11, 2025

Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects

Serena Omo‐Lamai, Yufei Wang, Manthan N. Patel…·Jacob Samuel Brenner

This paper identifies that lipid nanoparticle-induced inflammation arises from endosomal membrane damage and proposes strategies to mitigate it through galectin inhibition or ESCRT-recruiting lipids.

182 citationstop 1%

humanexperimental assay

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