Cancer BiologybioRxivPreprint
Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer
Xinyuan Tong, Ayushi S. Patel, Eejung Kim…·Hongbin Ji
The paper identifies adeno-to-squamous transition (AST) as a mechanism of resistance to KRAS inhibitors in LKB1 mutant lung cancer and links KRT6A expression to poor patient outcomes.
DOI 10.1101/2023.09.07.556567