BBSome-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue
Katharina Sieckmann, Nora Winnerling, Dalila Juliana Silva Ribeiro…·Dagmar Wachten
This study shows that primary cilia dysfunction in Bbs8-/- mice reduces adipose stem cells and promotes fibrogenic progenitors via disrupted Hedgehog signaling, affecting adipogenesis and lipid uptake.