Author

G. A. Roth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. C. Yu· 2 shared A. E. Powell· 2 shared B. Pulendran· 2 shared C. L. Maikawa· 2 shared E. A. Appel· 2 shared E. C. Gale· 2 shared A. A. A. Smith· 1 shared A. Buahin· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioengineering

A. C. Yu

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3 papers

Recent·Most cited

BioengineeringbioRxivMay 24, 2022

Subcutaneous delivery of an antibody against SARS-CoV-2 from a supramolecular hydrogel depot

C. M. Kasse, A. C. Yu, A. E. Powell…·E. A. Appel

This paper develops a supramolecular hydrogel depot for subcutaneous delivery of SARS-CoV-2 bnAbs, showing prolonged release and improved pharmacokinetics compared to standard administration.

DOI 10.1039/d2bm00819j

mouseexperimental assay

𝕏 PostBluesky

BioengineeringAdvanced MaterialsPeer-reviewedOct 14, 2021

Hydrogel-based slow release of a receptor-binding domain subunit vaccine elicits neutralizing antibody responses against SARS-CoV-2

E. C. Gale, A. E. Powell, G. A. Roth…·E. Appel

This study shows that slow release of an RBD subunit vaccine via hydrogel enhances neutralizing antibody responses against SARS-CoV-2 compared to bolus administration.

DOI 10.1002/adma.202104362

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BioengineeringbioRxivMay 26, 2020

Injectable hydrogels for sustained co-delivery of subunit vaccines enhance humoral immunity

G. A. Roth, E. C. Gale, M. Alcantara-Hernandez…·E. A. Appel

This paper introduces an injectable hydrogel platform for sustained co-delivery of subunit vaccines, which enhances humoral immunity by improving antigen and adjuvant presentation over time.

DOI 10.1021/acscentsci.0c00732

mouseexperimental assay

𝕏 PostBluesky