G. Ball

Quantifying spontaneous infant movements using state-space models

This study uses state-space models to analyze spontaneous infant movements, showing age-related changes and differences in high-risk infants.

PML mutants resistant to arsenic induced degradation fail to generate the appropriate SUMO and ubiquitin signals required for RNF4 and p97 recruitment

The paper investigates arsenic resistance in PML mutants by analyzing SUMO and ubiquitin signaling and their impact on RNF4 and p97 recruitment.

CbpD crystal structure adds intrigue to substrate-specificity motifs in chitin-active lytic polysaccharide monooxygenases

The paper reports the crystal structure of CbpD, revealing chitin-specific motifs and post-translational modifications, and highlights the utility of AI in structural prediction.

Founder cell configuration drives competitive outcome within colony biofilms

The paper shows that founder cell location and density determine competitive outcomes in biofilms, with spatial dynamics being the main driver of strain abundance.

Multidisciplinary Interrogation of a Crucial Protein Interface in the Type II Secretion System

The paper determines the structural role of XcpH in the T2SS by showing it bridges XcpIJK and XcpG, revealing its adapter function through unwinding of its N-terminal helix.

Pharmacological rescue of impaired mitophagy in Parkinson's disease-related LRRK2 G2019S knock-in mice

This study shows that the LRRK2 G2019S mutation impairs mitophagy in mice, and that LRRK2 inhibitors can rescue this defect, suggesting a potential therapy for Parkinson's disease.

Involvement of the Pseudomonas aeruginosa MexAB-OprM efflux pump in the secretion of the metallophore pseudopaline

This paper investigates the role of the MexAB-OprM efflux pump in pseudopaline secretion and recovery in Pseudomonas aeruginosa, revealing new functions for the pump and insights into metal release mechanisms.

FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning

This study identifies FAM83D as a scaffold that recruits CK1α to the mitotic spindle, ensuring proper spindle positioning and timely cell division.

Pseudopaline, a staphylopine-like metallophore involved in zinc and nickel uptake in Pseudomonas aeruginosa

This paper identifies pseudopaline, a staphylopine-like metallophore in Pseudomonas aeruginosa, involved in nickel and zinc uptake under metal scarce conditions.