Author

A. Whigham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Ahkter· 1 shared A. Allue Guardia· 1 shared A. B. Reitz· 1 shared A. Garcia Vilanova· 1 shared A. I. Lamond· 1 shared A. J. Brenes-Murillo· 1 shared A. Olmo-Fontanez· 1 shared A. R. Prescott· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Ahkter

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Compound FC-10696 Inhibits Egress and Spread of Marburg Virus

Z. Han, H. Ye, J. Liang, A. Shepley-McTaggart, J. E. Wrobel, A. B. Reitz, A. Whigham, K. N. Kavelish, M. S. Saporito, B. Freedman, O. Shtanko, R. N. Harty

The paper identifies FC-10696 as a novel compound that inhibits Marburg virus egress and spread, showing antiviral effects in cell cultures and animal models.

bioRxiv · Jan 15, 2021Microbiology

Lethality of SARS-CoV-2 infection in K18 human angiotensin converting enzyme 2 transgenic mice

F. Oladunni, J.-G. Park, P. Pino Tamayo, O. Gonzalez, A. Ahkter, A. Allue Guardia, A. Olmo-Fontanez, S. Gautam, A. Garcia Vilanova, C. Ye, K. Chiem, C. Headley, V. Dwivedi, L. Parodi, K. Alfson, , J. B. Torrelles

This study demonstrates that K18 hACE2 transgenic mice are susceptible to SARS-CoV-2 infection, exhibit cytokine and chemokine storms, and serve as a model for studying viral pathogenesis and therapeutic development.

bioRxiv · Jul 18, 2020Microbiology

FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning

L. J. Fulcher, Z. He, L. Mei, T. Macartney, N. Wood, A. R. Prescott, A. Whigham, J. Varghese, R. Gourlay, G. Ball, R. G. Clarke, D. G. Campbell, C. A. Maxwell, G. P. Sapkota

This study identifies FAM83D as a scaffold that recruits CK1α to the mitotic spindle, ensuring proper spindle positioning and timely cell division.

bioRxiv · Nov 27, 2018Cell Biology

Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS

T. Ly, A. Whigham, R. Clarke, A. J. Brenes-Murillo, B. Estes, P. Wadsworth, A. I. Lamond

The paper uses PRIMMUS to analyze proteomic changes during cell cycle progression, identifying phosphorylation sites and their roles in mitotic progression.

bioRxiv · Apr 9, 2017Biochemistry