Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells
P. Mistry, C. S. Boddupalli, G. Belinsky, J. Gans, E. Teeple, T.-H. Nguyen, S. Mehta, L. Guo, M. Kramer, J. Ruan, H. Wang, M. Davison, V. DJ, B. Zhang, K. Klinger, S. Nair
This study investigates neuroinflammation in neuronopathic Gaucher disease by examining microglia and NK cells in mouse models, showing that Gba rescue in these cells reduces neuroinflammation and improves survival.
bioRxiv · May 13, 2022Immunology