G. Coop

The promise and challenge of spatial inference with the full ancestral recombination graph underBrownian motion

The paper extends Brownian motion models to ancestral recombination graphs for spatial inference but finds biases in dispersal rate and ancestor location estimates due to discrepancies at recombination events.

Distinct ancient structural polymorphisms control heterodichogamy in walnuts and hickories

This paper identifies two ancient structural variants in walnut and hickory species that control heterodichogamy, a mating system with distinct genetic mechanisms in each genus.

The contribution of gene flow, selection, and genetic drift to five thousand years of human allele frequency change

This study decomposes the contributions of gene flow, genetic drift, and linked selection to allele frequency change over 5,000 years using ancient human DNA datasets.

The temporal and genomic scale of selection following hybridization

This paper develops wavelet-based methods to analyze local ancestry variation in hybrid populations and finds that selection against introgressed alleles affects up to 20% of genomic variation.

Polygenic outcomes of sexually antagonistic selection

This study examines how polygenic phenotypes evolve under sexually antagonistic selection, showing rapid divergence toward sex-specific optima and the role of sex chromosomes in shaping phenotypic variance.

A complex evolutionary history of genetic barriers to gene flow in hybridizing warblers

This study investigates genetic barriers to gene flow in hybridizing warblers, identifying long-lasting and recent selective sweeps in specific genomic regions.

Population differentiation of polygenic score predictions under stabilizing selection

This study shows that stabilizing selection on complex traits increases genetic differentiation at GWAS loci, reducing polygenic score accuracy in unrepresented populations and overestimating phenotypic differences.

Mate choice enhances post-zygotic barriers to gene flow via ancestry bundling

The paper shows mate choice enhances post-zygotic barriers to gene flow by bundling ancestry in offspring, increasing purging of introgressed DNA through increased ancestry variance.

Estimating dispersal rates and locating genetic ancestors with genome-wide genealogies

This study estimates dispersal rates and locates genetic ancestors using genome-wide genealogies in Arabidopsis thaliana.

Selective sorting of ancestral introgression in maize and teosinte along an elevational cline

This study examines introgression patterns between maize and mexicana teosinte across an elevational gradient, finding ancient introgression from mexicana into maize that contributes to adaptation to high elevation environments.

The timing of human adaptation from Neanderthal introgression

This study examines the timing of selection on Neanderthal introgressed alleles in modern humans, identifying cases where these alleles were quickly beneficial or persisted for later selection.

Estimating the genome-wide contribution of selection to temporal allele frequency change

The paper estimates the genome-wide contribution of selection to temporal allele frequency change using covariance analysis in selection experiments, finding 17-37% of change driven by selection.

Genetic signatures of evolutionary rescue by a selective sweep

This study extends the hitch-hiking model to evolutionary rescue, showing how demographic feedback affects genetic signatures compared to constant population size sweeps.

Selection and hybridization shaped the rapid spread of African honey bee ancestry in the Americas

The paper maps the spread of African honey bee ancestry in the Americas using genome sequencing and identifies genomic regions associated with climate adaptation and fitness traits.

The Linked Selection Signature of Rapid Adaptation in Temporal Genomic Data

This paper develops a method to estimate additive genetic variation and population parameters from temporal genomic data by analyzing autocovariances caused by linked selection.

Polygenic Adaptation has Impacted Multiple Anthropometric Traits

The paper investigates polygenic adaptation in anthropometric traits across global populations but finds replication issues in height-related results due to stratification problems in datasets.

Population genomics perspectives on convergent adaptation

This paper discusses convergent adaptation and outlines a framework to assess its significance using population genomics approaches.

Reduced signal for polygenic adaptation of height in UK Biobank

The paper analyzes polygenic height scores from UK Biobank and finds reduced signals of selection compared to previous studies, suggesting potential issues with population stratification correction.

Detecting adaptive differentiation in structured populations with genomic data and common gardens

The paper develops methods to detect polygenic adaptation using genomic data and common garden trait measurements in structured populations, applying them to maize lines and landraces.

Reconstructing the history of polygenic scores using coalescent trees

The paper develops methods to estimate the historical time course of polygenic scores using coalescent trees, revealing evidence of natural selection on human height.

Allele frequency dynamics in a pedigreed natural population

This study uses pedigree and genomic data from Florida Scrub-Jays to analyze how genetic drift, selection, and gene flow influence allele frequency changes over time.

Distinguishing among modes of convergent adaptation using population genomic data

This paper develops a statistical method to detect and distinguish modes of convergent adaptation using population genomic data, applying it to cases of copper tolerance and pollutant tolerance in plants and fish.

Inferring Continuous and Discrete Population Genetic Structure Across Space

The paper introduces a statistical framework to infer both continuous and discrete population genetic structure, demonstrating its effectiveness through simulations and empirical datasets.

Deconstructing isolation-by-distance: the genomic consequences of limited dispersal

The paper investigates how limited dispersal in Florida Scrub-Jays shapes fine-scale genetic structure, showing stronger isolation-by-distance in males due to sex-specific dispersal patterns.

Population-genomic inference of the strength and timing of selection against gene flow

The paper infers the strength and timing of selection against gene flow using DNA polymorphism data and recombination rate variation in Mimulus guttatus.