G. E. Thwaites

This study examines rifampicin tolerance in isoniazid-resistant Mycobacterium tuberculosis isolates, finding increased tolerance and faster growth in resistant strains, which may contribute to multidrug-resistant TB emergence.

The paper investigates the distribution of Mycobacterium tuberculosis Lineage 4 in Southeast Asia using genomic data, finding that most L4 sub-clades in the region have no recent European origin and may involve China as an intermediate.

The study shows that the virulence of the Cryptococcus neoformans VNIa-5 lineage varies based on isolate source and can be induced through secreted proteins in extracellular vesicles.

This study compares the virulence of Cryptococcus neoformans ST5 and non-ST5 isolates in HIV-infected and uninfected patients in Vietnam, finding ST5 isolates show greater variability and initial inflammatory response but lower fungal burden in mice.

This study tracks the emergence of ciprofloxacin-resistant Shigella sonnei in Vietnam, showing that resistance plasmids are transferred from commensal E. coli via horizontal gene transfer, facilitated by ciprofloxacin use.

This study identifies CSF pro-resolving mediator profiles and 5-lipoxygenase activity as correlates of disease severity and 80-day survival in adults with tuberculous meningitis.