ImmunologybioRxiv
Efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion
C. M. Le Gall, A. Cammarata, L. de Haas…·M. Verdoes
This study demonstrates that targeting NY-ESO-1 antigen to human cDC1s via XCL1(CC3) enhances cross-presentation and CD8+ T cell activation.
DOI 10.1136/jitc-2021-004309