BiophysicsbioRxiv
Structural basis for receptor selectivity and inverse agonism in S1P5 receptors
E. Lyapina, E. Marin, A. Gusach…·V. Cherezov
The paper presents a high-resolution structure of the S1P5 receptor complexed with an inverse agonist, revealing structural features that explain receptor subtype selectivity and inverse agonism.
DOI 10.1038/s41467-022-32447-1