Author

G. Lustig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Assay:proteomics· 1

Frequent Co-Authors

A. Sigal· 4 shared J. Giandhari· 3 shared S. Cele· 3 shared T. de Oliveira· 3 shared L. Jackson· 2 shared Y. Ganga· 2 shared A. Derache· 1 shared A. K. Shalek· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersMicrobiology

A. Sigal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Aggregated Mycobacterium tuberculosis enhances the inflammatory response

A. Sigal, H. Rodel, I. M. Ferreira, C. Ziegler, Y. Ganga, M. Bernstein, S.-H. Hwa, G. Kaplan, G. Lustig, K. Nargan, M. Noursadeghi, A. Steyn, A. K. Shalek

The paper investigates how aggregated Mycobacterium tuberculosis triggers a stronger inflammatory response in macrophages compared to single or multiple non-aggregated bacilli.

bioRxiv · Mar 23, 2021Microbiology

HIV cell-to-cell spread slows evolution of drug resistance

J. Hunter, S. Cele, L. Jackson, J. Giandhari, T. de Oliveira, G. Lustig, A. Sigal

This study shows that HIV cell-free infection accelerates the evolution of drug resistance compared to cell-to-cell spread, with cell-free infection enabling multidrug resistance in the presence of two reverse transcriptase inhibitors.

bioRxiv · Sep 4, 2020 · PreprintEvolutionary Biology

Complementation can maintain a quasispecies of drug sensitive and resistant HIV

L. Jackson, S. Cele, G. Lustig, J. Giandhari, T. de Oliveira, R. Neher, A. Sigal

The paper shows that complementation between drug-sensitive and resistant HIV genotypes maintains a stable quasispecies, preventing the resistant genotype from outcompeting the sensitive one.

bioRxiv · Apr 20, 2020 · PreprintEvolutionary Biology

The CNS in the face of ART contains T cell origin HIV which can lead to drug resistance

G. Lustig, S. Cele, F. Karim, Y. Ganga, K. Khan, B. Gosnell, Y. Moosa, R. Harrichandparsad, S. Marais, R. Gupta, A. Derache, J. Giandhari, T. de Oliveira, K. Govender, J. Adamson, , A. Sigal

The paper investigates the origin of HIV in the CNS of ART-suppressed individuals and finds T cell-derived HIV that can lead to drug resistance.

bioRxiv · Mar 25, 2019 · PreprintMicrobiology