G. Panis

Regulation of the transcription factor CdnL promotes adaptation to nutrient stress in Caulobacter

This study shows that CdnL is downregulated during the stringent response in Caulobacter, and its clearance is essential for adaptation to nutrient fluctuations.

β-helical protein PerA orchestrates antibiotic uptake across the Caulobacter outer membrane via converging stress signaling systems

The paper shows that PerA, a β-helical protein in Caulobacter crescentus, regulates antibiotic uptake by modulating TBDRs and stress response pathways.

Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals genetic requirement for virulence and survival in amoebae and microglial cells

This study uses Tn-Seq to identify essential genes for Mycobacterium marinum survival in amoebae and microglial cells, revealing metabolic and virulence gene requirements during infection.

Co-chaperone-mediated post-translational control of efflux pump induction underlies adaptive β-lactam resistance in Caulobacter crescentus.

The CTPase activity of ParB acts as a timing mechanism to control the dynamics and function of prokaryotic DNA partition complexes

This study identifies how ParB's CTPase activity regulates DNA partition complex dynamics and function by controlling clamp sliding time and spreading.

Molecular architecture of the DNA-binding sites of the P-loop ATPases MipZ and ParA from Caulobacter crescentus

This study identifies the DNA-binding residues of MipZ and ParA from Caulobacter crescentus, revealing sequence-independent electrostatic interactions and conserved binding mechanisms across ParA-like ATPases.

Bypass of an epigenetic S-phase transcriptional module by convergent nutrient stress signals

The paper shows that phosphate deprivation and (p)ppGpp stress signals bypass the GcrA/CcrM module to activate S-phase transcription in Caulobacter crescentus.

Bacterial cell cycle and growth phase switch by the essential transcriptional regulator CtrA

The paper identifies a conserved determinant in CtrA that controls promoter switching during the bacterial cell cycle, linking it to growth phase transitions and virulence.

A bifunctional ATPase drives tad pilus extension and retraction

This study identifies a bifunctional ATPase, CpaF, that drives both extension and retraction of tad pili in Caulobacter crescentus through ATP hydrolysis.

A Novel DNA-binding Protein Coordinates Asymmetric Chromosome Replication and Chromosome Partitioning

This paper identifies OpaA, a novel DNA-binding protein in Caulobacter crescentus that coordinates chromosome replication initiation and early partitioning.