Universal recording of cell-cell contacts in vivo for interaction-based transcriptomics
S. Nakandakari-Higa, M. C. C. Canesso, S. Walker, A. Chudnovskiy, J. Bilanovic, J. T. Jacobsen, S. M. Parigi, K. Fiedorczuk, E. Fuchs, A. M. Bilate, G. Pasqual, D. Mucida, Y. Pritykin, G. D. Victora
The paper introduces uLIPSTIC, a universal method to record cell-cell interactions in vivo, and combines it with single-cell transcriptomics to study immune cell interactions with intestinal epithelial cells.
bioRxiv · Mar 16, 2023Immunology