Myeloid A20 is critical for type-2 immune mediated helminth resistance
I. Petta, M. Thorp, m. Ciers, G. Blancke, L. Boon, T. Meese, F. Van Nieuwerburgh, A. Wullaert, R. K. Grencis, D. Elewaut, G. van Loo, L. Vereecke
This study identifies A20 as an essential myeloid factor for inducing type-2 immune responses against Trichuris muris, with its loss leading to chronic infection and inflammation.
bioRxiv · Sep 5, 2023 · PreprintImmunology