Author

H. C. Lane

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Organism:virus· 1

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H. Highbarger· 1 shared H. Sui· 1 shared J. G. Bernbaum· 1 shared J. Yang· 1 shared M. Hao· 1 shared Q. Chen· 1 shared R. Dewar· 1 shared S. Laverdure· 1 shared

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H. Highbarger

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1 paper

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedNov 9, 2021

Natural Occurring Non-Synonymous Single Nucleotide Polymorphisms in Integrase and RNase H Regulate Assembly and Autoprocessing of HIV-1

T. Imamichi, J. G. Bernbaum, S. Laverdure…·H. C. Lane

This paper investigates the impact of 14 non-synonymous SNPs in HIV on viral fitness, finding that specific mutations in integrase and RNase H impair GagPol autoprocessing and replication.

DOI 10.1128/jvi.01323-21

virusexperimental assay

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