Author

H. Friberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Assay:scRNA-seq· 4 Research Focus:differential expression· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

J. R. Currier· 5 shared K. Victor· 4 shared A. L. Rothman· 3 shared A. T. Waickman· 3 shared T. Li· 3 shared A. Srikiatkhachorn· 2 shared A. Waickman· 2 shared H. Siegfried· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersImmunology

J. R. Currier

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Author profile →

5 papers

Recent·Most cited

mRNA-1273 vaccination protects against SARS-CoV-2 elicited lung inflammation in non-human primates

A. T. Waickman, K. Victor, K. L. Newell, T. L. Li, H. Friberg, K. Foulds, M. Roederer, D. L. Bolton, J. R. Currier, R. Seder

mRNA-1273 vaccination reduces lower respiratory tract inflammation in SARS-CoV-2 challenged rhesus macaques by limiting viral replication and inflammatory gene expression.

bioRxiv · Dec 24, 2021Immunology

Monomeric IgA antagonizes IgG-mediated enhancement of DENV infection

A. Wegman, H. Fang, A. L. Rothman, S. J. Thomas, T. P. Endy, M. K. McCracken, J. R. Currier, H. Friberg, G. D. Gromowski, A. T. Waickman

This study shows that monomeric IgA can neutralize DENV and block IgG-mediated antibody-dependent enhancement (ADE) in vitro.

bioRxiv · Sep 14, 2021Immunology

Temporally integrated single cell RNA sequencing analysis of controlled and natural primary human DENV-1 infections

A. Waickman, H. Friberg, G. Gromowski, W. Rutvisuttinunt, T. Li, H. Siegfried, K. Victor, M. McCracken, S. Fernandez, A. Srikiatkhachorn, D. Ellison, R. G. Jarman, S. Thomas, A. L. Rothman, T. Endy, J. R. Currier

The paper compares the transcriptional responses of controlled and natural primary DENV-1 infections using scRNA-seq, finding similar inflammatory responses but more pronounced suppression of translation and mitochondrial function in natural infections.

bioRxiv · Jul 16, 2020Immunology

Analysis of cell-associated DENV RNA by oligo(dT) primed 5' capture scRNAseq

M. A. Sanborn, T. Li, K. Victor, H. Siegfried, C. Fung, A. L. Rothman, A. Srikiatkhachorn, S. Fernandez, D. W. Ellison, R. Jarman, H. Friberg, I. Maljkovic Berry, J. R. Currier, A. Waickman

This study uses 5' capture scRNAseq to detect and quantify DENV RNA in infected cells, revealing viral sequence variability and identifying infected cell types.

Scientific Reports · Jun 3, 2020Peer-reviewedMicrobiology

Dissecting the heterogeneity of DENV vaccine-elicited cellular immunity using single-cell RNA sequencing and cellular metabolic profiling

A. T. Waickman, K. Victor, T. Li, K. Hatch, W. Rutvisuttinnunt, C. Medin, B. Gabriel, R. G. Jarman, H. Friberg, J. R. Currier

This study uses single-cell RNA sequencing and metabolic profiling to identify metabolic signatures of durable T cell memory in DENV vaccine responses.

bioRxiv · Jan 3, 2019Immunology