Author

R. Seder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:non-human primate· 5 Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. F. Haynes· 3 shared C. T. DeMarco· 3 shared D. C. Montefiori· 3 shared D. Li· 3 shared D. R. Martinez· 3 shared D. Weissman· 3 shared E. Lee· 3 shared G. D. Sempowski· 3 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

B. F. Haynes

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Antibody-mediated depletion of select T cell subsets in blood and tissue of nonhuman primates

M. S. Sutton, A. N. Bucsan, C. C. Lehman, M. Kamath, S. Pokkali, D. M. Magnani, R. Seder, P. A. Darrah, M. Roederer

The paper evaluates the depletion of T cell subsets in nonhuman primates using monoclonal antibodies, finding substantial depletion in blood and tissue with residual cells often remaining in tissue.

bioRxiv · Dec 22, 2023 · PreprintImmunology

Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates

R. D. Malewana, V. Stalls, A. May, X. Lu, D. R. Martinez, A. Schafer, D. Li, M. Barr, L. L. Sutherland, E. Lee, R. Parks, W. E. Beck, A. Newman, K. W. Bock, M. Minai, , K. O. Saunders

Non-stabilized SARS-CoV-2 Spike mRNA vaccination in macaques induces B cell lineages targeting conserved epitopes on Omicron variants or cross-neutralizing epitopes on Sarbecoviruses.

bioRxiv · Dec 18, 2023 · PreprintImmunology

Protective intravenous BCG vaccination induces enhanced immune signaling in the airways

J. M. Peters, E. B. Irvine, J. M. Rosenberg, M. H. Wadsworth, T. K. Hughes, M. Sutton, S. K. Nyquist, J. D. Bromley, R. Mondal, M. Roederer, R. Seder, P. A. Darrah, J. L. Flynn, A. K. Shalek, S. M. Fortune, B. D. Bryson

This study shows that high-dose IV BCG vaccination in rhesus macaques enhances airway immune signaling and cellular responses, improving protection against Mtb.

bioRxiv · Jul 16, 2023 · PreprintImmunology

Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine

D. Li, D. R. Martinez, A. Schäfer, H. Chen, M. Barr, L. L. Sutherland, E. Lee, R. Parks, D. Mielke, W. Edwards, A. Newman, K. W. Bock, M. Minai, B. M. Nagata, M. Gagne, , B. F. Haynes

This study shows a nanoparticle vaccine induces broad neutralizing antibodies against multiple SARS-CoV-2 variants and protects non-human primates and mice from viral challenges.

bioRxiv · Jan 26, 2022Immunology

mRNA-1273 vaccination protects against SARS-CoV-2 elicited lung inflammation in non-human primates

A. T. Waickman, K. Victor, K. L. Newell, T. L. Li, H. Friberg, K. Foulds, M. Roederer, D. L. Bolton, J. R. Currier, R. Seder

mRNA-1273 vaccination reduces lower respiratory tract inflammation in SARS-CoV-2 challenged rhesus macaques by limiting viral replication and inflammatory gene expression.

bioRxiv · Dec 24, 2021Immunology

Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice

K. Wu, A. Choi, M. Koch, S. Elbashir, L. Ma, D. Lee, A. Woods, C. Henry, C. Palandjian, A. Hill, H. Jani, J. Quinones, N. Nunna, S. O'Connell, A. B. McDermott, , D. K. Edwards

This study evaluates updated SARS-CoV-2 mRNA vaccines in mice, showing that mRNA-1273.351 boosts neutralization against B.1.351 and mRNA-1273.211 provides broad cross-variant protection.

bioRxiv · Apr 13, 2021Microbiology

SARS-CoV-2 vaccination induces neutralizing antibodies against pandemic and pre-emergent SARS-related coronaviruses in monkeys

K. O. Saunders, E. Lee, R. Parks, D. R. Martinez, D. Li, H. Chen, R. J. Edwards, S. M. C. Gobeil, M. Barr, K. Mansouri, S. M. Alam, L. L. Sutherland, F. Cai, A. Sanzone, M. Berry, , B. F. Haynes

This study shows that SARS-CoV-2 vaccines induce neutralizing antibodies against SARS-CoV-1, SARS-CoV-2, and batCoVs in monkeys.

bioRxiv · Feb 17, 2021 · PreprintImmunology