Diverse Gut Pathogens Exploit the Host Engulfment Pathway via a Conserved Mechanism
M. S. Anandachar, S. Roy, S. Sinha, B. Agyekum, S.-R. Ibeawuchi, H. Gementera, A. Amamoto, G. D. Katkar, P. Ghosh
The paper identifies a conserved molecular interface between WxxxE-effector proteins from gut pathogens and the host protein ELMO1, showing how pathogens exploit the host's engulfment pathway.
bioRxiv · Apr 9, 2023Immunology