Author

H. Hashemi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

C. E. Stebbins· 3 shared F. N. Papavasiliou· 3 shared M. van Straaten· 3 shared A. Hempelmann· 2 shared J. Zeelen· 2 shared A. Baumann· 1 shared A. Miller· 1 shared A. Mohammadnia· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersMicrobiology

C. E. Stebbins

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An Epitope-Focused Trypanosome-Derived Vaccine Platform Elicits High-Affinity Antibodies and Immunity Against Fentanyl Effects

G. Triller, E. P. Vlachou, H. Hashemi, M. van Straaten, J. Zeelen, Y. Kelemen, C. Baehr, C. Marker, S. Ruf, A. Svirina, S. Kruse, A. Baumann, A. Miller, M. Bartel, M. Pravetoni, , J. P. Verdi

This paper develops a trypanosome-derived vaccine platform (VAST) that elicits high-affinity antibodies against fentanyl, demonstrating protective immunity through single-cell RNAseq and crystallography.

bioRxiv · May 2, 2022 · PreprintImmunology

Nanobody Mediated Macromolecular Crowding Induces Membrane Fission and Remodeling in the African Trypanosome

A. Hempelmann, L. Hartleb, M. Van Straaten, H. Hashemi, J. P. Zeelen, F. N. Papavasiliou, M. Engstler, C. E. Stebbins, N. G. Jones

The paper shows that nanobodies induce membrane fission and remodeling in African trypanosomes by causing macromolecular crowding, leading to loss of motility and nanovesicle shedding.

bioRxiv · Jan 13, 2021Microbiology

Integrated analysis of high throughput transcriptomic data revealed specific gene expression signature of cardiomyocytes

M. R. Omrani, E. Sharifi, N. Khazaei, S. Jahangiri Esfahani, N. W. Kieran, H. Hashemi, A. Mohammadnia, M. Yaqubi

This study identifies a 118-gene transcriptomic signature of human and mouse cardiomyocytes through integrated analysis of bulk RNA-seq, scRNA-seq, and microarray data, revealing differences between primary and differentiated cardiomyocytes.

bioRxiv · Jun 14, 2020 · PreprintCell Biology

A Parasite Coat Protein Binds Suramin to Confer Drug Resistance

J. Zeelen, M. van Straaten, J. Verdi, A. Hempelmann, H. Hashemi, K. Perez, P. D. Jeffrey, S. Haelg, N. Wiedemar, P. Maeser, F. N. Papavasiliou, C. E. Stebbins

This study identifies that the trypanosome VSGsur protein binds suramin, conferring drug resistance, and shows this interaction is critical for resistance.

bioRxiv · Jun 4, 2020 · PreprintMicrobiology