Author

C. Baehr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

M. Pravetoni· 3 shared D. Hicks· 2 shared G. T. Hart· 2 shared J. A. Sangala· 2 shared J. K. Dick· 2 shared M. C.-J. Cheeran· 2 shared V. D. Krishna· 2 shared A. Baumann· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

M. Pravetoni

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ACE2 decoy Fc-fusions and bi-specific killer engager (BiKEs) require Fc engagement for in vivo efficacy against SARS-CoV-2

J. K. Dick, D. Hicks, V. D. Krishna, J. A. Sangala, B. T. Zandstra, C. Baehr, J. S. Verbeek, M. S. Cragg, M. C.-J. Cheeran, M. Pravetoni, G. T. Hart

This study shows that Fc receptor engagement is necessary for the efficacy of SARS-CoV-2 therapeutics, including mAbs and BiKEs, and demonstrates the effectiveness of ACE2 decoy Fc-fusions and BiKEs against multiple variants.

bioRxiv · Jun 20, 2024 · PreprintImmunology

Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C)

J. K. Dick, J. A. Sangala, V. D. Krishna, A. Khaimraj, L. Hamel, S. M. Erickson, D. Hicks, Y. Soigner, L. E. Covill, A. Johnson, M. J. Ehrhardt, K. Ernste, P. Brodin, R. A. Koup, A. Khaitan, , G. T. Hart

This study identifies dysregulated antibody-mediated cellular responses in MIS-C, linking NK cell dysfunction to immune pathology and suggesting potential therapeutic interventions.

bioRxiv · Apr 16, 2024Immunology

An Epitope-Focused Trypanosome-Derived Vaccine Platform Elicits High-Affinity Antibodies and Immunity Against Fentanyl Effects

G. Triller, E. P. Vlachou, H. Hashemi, M. van Straaten, J. Zeelen, Y. Kelemen, C. Baehr, C. Marker, S. Ruf, A. Svirina, S. Kruse, A. Baumann, A. Miller, M. Bartel, M. Pravetoni, , J. P. Verdi

This paper develops a trypanosome-derived vaccine platform (VAST) that elicits high-affinity antibodies against fentanyl, demonstrating protective immunity through single-cell RNAseq and crystallography.

bioRxiv · May 2, 2022 · PreprintImmunology