Author

H. J. Donnella

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Cancer Biology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Goga· 1 shared J. Gordan· 1 shared J. Korkola· 1 shared J. T. Webber· 1 shared K. M. Shokat· 1 shared K. N. Shah· 1 shared N. Bayani· 1 shared O. Momcilovic· 1 shared

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2017-2017 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Goga

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1 paper

Recent·Most cited

Cancer BiologybioRxivJun 30, 2017

Kinome rewiring reveals AURKA is a molecular barrier to the efficacy of PI3K/mTOR-pathway inhibitors in breast cancer

H. J. Donnella, J. T. Webber, R. S. Levin…·S. Bandyopadhyay

The paper identifies AURKA as a barrier to PI3K/mTOR inhibitor efficacy in breast cancer by mapping kinome dynamics and showing that AURKA inhibition synergizes with these drugs to induce apoptosis and tumor regression.

DOI 10.1038/s41589-018-0081-9

humanproteomics

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