Author

H. J. Painter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:human· 3 Organism:plant (other)· 2 Approach:statistical model· 2 Research Focus:transcription & RNA processing· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

M. Llinas· 5 shared L. M. Orchard· 2 shared A. B. Vaidya· 1 shared A. Sebastian· 1 shared C. Luck· 1 shared G. A. Josling· 1 shared I. Albert· 1 shared J. D. Storey· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersMicrobiology

M. Llinas

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5 papers

Recent·Most cited

The PfAP2-G2 transcription factor is a critical regulator of gametocyte maturation

S. Singh, J. M. Santos, L. M. Orchard, N. Yamada, R. van Biljon, H. J. Painter, S. Mahony, M. Llinas

This study identifies PfAP2-G2 as a critical transcription factor for Plasmodium falciparum gametocyte maturation, showing it regulates gene expression and interacts with chromatin remodeling proteins.

bioRxiv · Oct 27, 2020Microbiology

Atypical molecular basis for drug resistance to mitochondrial function inhibitors in Plasmodium falciparum

H. J. Painter, J. M. Morrisey, M. W. Mather, L. M. Orchard, C. Luck, M. J. Smilkstein, M. K. Riscoe, A. B. Vaidya, M. Llinas

This study identifies a novel mechanism of drug resistance in Plasmodium falciparum involving copy number variation and a SNP in pfdhodh, leading to pan-resistance to mtETC and DHODH inhibitors.

bioRxiv · Oct 8, 2020Microbiology

Regulation of sexual differentiation is linked to invasion in malaria parasites

G. A. Josling, J. Venezia, L. Orchard, T. J. Russell, H. J. Painter, M. Llinas

The paper shows PfAP2-G activates gametocyte genes and also promotes red blood cell invasion genes, linking sexual differentiation to invasion in malaria parasites.

bioRxiv · Feb 8, 2019 · PreprintMicrobiology

Real-time in vivo Global Transcriptional Dynamics During Plasmodium falciparum Blood-stage Development

H. J. Painter, N. C. Chung, A. Sebastian, I. Albert, J. D. Storey, M. Llinas

This study uses 4-TU labeling to track real-time transcription dynamics of Plasmodium falciparum during its blood-stage development, revealing transcription timing and stabilization patterns across the IDC.

bioRxiv · Feb 14, 2018Microbiology

Capturing in vivo RNA transcriptional dynamics from the malaria parasite P. falciparum

H. J. Painter, M. Carrasquilla, M. Llinas

This paper develops a method to capture in vivo RNA transcriptional dynamics in Plasmodium falciparum by engineering parasites to salvage pyrimidines and label nascent mRNAs, revealing transcriptional reprogramming during gametocyte stage transition.

bioRxiv · Jan 12, 2017Microbiology