BiochemistrybioRxiv
Insight into glycosphingolipid crypticity: Crystal structure of the anti-tumor antibody 14F7 and recognition of NeuGc GM3 ganglioside
K. Bjerregaard-Andersen, H. Johannesen, F. Abraha…·U. Krengel
This paper presents the crystal structure of the 14F7 antibody bound to NeuGc GM3 and shows how membrane composition and curvature influence its binding.
DOI 10.1093/glycob/cwab076